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HEOR · STROBE

Real-World Evidence and Outcomes Research

Clinical trials show what an intervention can do under controlled conditions. Real-world evidence shows what it actually does in routine care, and payers increasingly want both. EvySaif designs and reports real-world evidence and outcomes research that complements trial data with how interventions perform across real populations, costs, and patient experience.

STROBEEHR, registries & claimsPROs & QoLHCRU & burden
Evidence · Real World
SourcesEHR, registries, claims data
DesignObservational study protocols
MeasureOutcomes, PROs, and costs
ReportTo the STROBE standard
The Pathway

Evidence from the real world, reported to standard

Real-world evidence is generated from data collected outside the randomised trial setting: electronic records, registries, claims and administrative databases, and prospective observational cohorts. Observational work is reported to the STROBE standard for transparency, so the methods and limitations are clear and the findings are credible to payers and journals alike.

Draw from real-world data

Electronic health records, registries, claims and administrative databases, and prospective observational cohorts, analysed to show how an intervention performs in routine care.

EHRRegistriesClaims

Design the study

Non-interventional and observational study design and protocols, including retrospective database analyses, chart reviews, and registry studies.

RetrospectiveChart reviewRegistry

Capture the humanistic dimension

Validated patient-reported outcome (PRO) and quality-of-life instruments capture the patient-experience dimension of value alongside the clinical outcomes.

PROsQuality of life

Measure the economics, then report

Healthcare resource utilisation, cost-of-illness, burden-of-disease, and epidemiology analyses complete the picture, reported in STROBE-aligned study reports and manuscripts.

HCRUCost of illnessSTROBE
At a Glance
Reporting standardSTROBE
Data sourcesEHR, registries, claims, cohorts
DesignsRetrospective and prospective
Patient experienceValidated PRO and QoL instruments
EconomicsHCRU and cost-of-illness studies
FeedsEconomic models and value dossiers

Evidence that works across the value story: real-world evidence feeds directly into the economic models and value dossiers we build, so the evidence you generate works across your whole value story rather than sitting in isolation.

Deliverables

What we prepare

Study design and protocolsObservational and non-interventional studies.

Database analysesRetrospective database and claims analyses.

Chart and registry studiesChart review and registry study support.

PRO and QoL studiesPatient-reported outcome and quality-of-life study design.

Economic studiesHealthcare resource utilisation and cost-of-illness studies.

Burden and reportingBurden-of-disease and epidemiology analyses, with STROBE-aligned reports and manuscripts.

Partnership

How EvySaif helps

We design the observational study and protocol, support data collection, and conduct and report the analysis. Studies are designed with clinically meaningful endpoints, handled with methodological care, and reported transparently to recognised standards.

Design observational studies with meaningful endpoints
Analyse real-world data with methodological care
Incorporate validated PRO and QoL instruments
Report to STROBE, for payers and journals alike

Why EvySaif

EvySaif is one of the best research and medical writing consultancies in India, and it shows in the quality of every deliverable. Outcomes research sits naturally alongside our clinical background. We design studies with clinically meaningful endpoints, handle the data with methodological care, and report transparently to recognised standards.

Questions

Frequently asked questions

Evidence derived from real-world data, meaning data collected outside controlled trials, such as electronic health records, registries, claims databases, and observational cohorts, analysed to show how an intervention performs in routine care.

Both. We can design the observational study and protocol, support data collection, and conduct and report the analysis.

Yes. We incorporate validated PRO and quality-of-life instruments to capture the patient-experience dimension of value.

Have a different question?

Tell us about your product, market, and timeline, and a clinician on our team will reply with specifics rather than a sales script.

Request a proposal
Last updated: July 2026. Regulatory forms, portals, and timelines change; specifics are re-verified periodically.

Building real-world evidence?

Tell us about your data sources and question, and we will come back with a scoped RWE or outcomes research quote.

Request a proposal