Global value dossiers that make the evidence case once, for every market
Global value dossier development from a clinician led team serving India, MENA, Europe, and global markets.
A global value dossier (GVD) is the master evidence document behind every market access conversation: the disease burden, the unmet need, the clinical evidence, the economic case, and the value messages, each substantiated and referenced so local teams adapt rather than reinvent. Built well, one GVD feeds HTA submissions, payer negotiations, AMCP dossiers, and internal training for years.
EvySaif builds GVDs from the evidence up. Value messages are written only after the systematic literature review and the economic analysis define what the data can support, which is the difference between a dossier payers engage with and one they discount on page one. The same team delivers the components: systematic reviews, cost-effectiveness models reported to CHEERS 2022, budget impact analyses, and the HTA submissions the dossier ultimately serves.
What we deliver
Full global value dossiers
Complete GVDs with substantiated value messages, evidence tables, and gap analyses, maintained as living documents as new data reads out.
AMCP format dossiers
US formulary dossiers to the current AMCP format, built from the same evidence base as the global document.
Local adaptation packages
Market adaptation kits for priority countries, mapping which inputs, comparators, and messages need localization, including for Gulf markets where economic evidence requirements are formalizing.
Objection handlers and payer tools
Payer facing summaries, objection handlers, and internal training materials derived from the dossier so field teams say what the evidence supports.
Built to the standards that matter
Frequently asked questions
When should a GVD be developed?
Ideally beginning around phase 3, so evidence gaps the dossier exposes can still be addressed before launch, with structured updates at each major data readout.
How is a GVD different from an HTA submission?
The GVD is the global master source; HTA submissions are market specific arguments built from it against local methods guides and comparators. We build both, which keeps them consistent.
Can you update or repair an existing dossier?
Yes. Dossier remediation, from re-substantiating value messages to rebuilding the economic section, is a substantial share of our HEOR work.