Zirabev

Bevacizumab biosimilar developed by Pfizer, development code PF-06439535. Reference product Avastin.

Brands by market: Zirabev (USA, EU, UAE) · Commercial partner or holder: Pfizer
FDAJun 2019approved
EMAFeb 2019authorised
CDSCOnot listed
EDEDec 2020registered

Status by market

FDA

United States · Zirabev

US Food and Drug AdministrationApproved
Brand
Zirabev
Holder or applicant
Pfizer Inc.
Pathway
351(k)
Approved
Jun 2019
Application or permission
761099
Licence type
351(k) biosimilar, not interchangeable
Presentations
100 mg/4 mL, 400 mg/16 mL
Source
S001, S016
EMA

European Union · Zirabev

European Medicines Agency and European CommissionApproved
Brand
Zirabev
Holder or applicant
Pfizer Europe MA EEIG
Pathway
Centralised (Article 10(4))
Approved
Feb 2019
Application or permission
EMEA/H/C/004697
Presentations
see SmPC
Source
S017
CDSCO

India

Not listed by CDSCO.

EDE

United Arab Emirates · Zirabev

Emirates Drug EstablishmentRegistered
Brand
Zirabev
Holder or applicant
Pfizer Service Company BVBA, Belgium · UAE supplier Gulf Drug LLC
Pathway
Registered medical product
Registered
Dec 2020
Presentations
100 mg/4 mL, 400 mg/16 mL
Source
S018

Chronology

Sources

All bevacizumab biosimilars

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Data current to September 2026.