Opuviz

Aflibercept biosimilar developed by Samsung Bioepis, development code SB15. Reference product Eylea.

Brands by market: Opuviz (USA, EU) · Commercial partner or holder: Biogen (USA, EU)
FDAMay 2024approved
EMANov 2024authorised
CDSCOnot listed
EDEnot listed

Status by market

FDA

United States · Opuviz

US Food and Drug AdministrationApproved
Brand
Opuviz
Holder or applicant
Samsung Bioepis Co., Ltd.
Pathway
351(k)
Approved
May 2024
Application or permission
761350
Licence type
351(k) interchangeable, designated May 2024
Presentations
2 mg/0.05 mL vial and PFS
Source
S001, S016
EMA

European Union · Opuviz

European Medicines Agency and European CommissionApproved
Brand
Opuviz
Holder or applicant
Samsung Bioepis NL B.V.
Pathway
Centralised (Article 10(4))
Approved
Nov 2024
Application or permission
EMEA/H/C/006056
Presentations
see SmPC
Source
S017
CDSCO

India

Not listed by CDSCO.

EDE

United Arab Emirates

Not listed by EDE.

Chronology

Sources

All aflibercept biosimilars

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Data current to September 2026.